Interleukin-17A (IL-17A), also known as CTLA-8, is apro-inflammatory cytokine member of a six-species family ofproteins (IL-17A-17F). IL-17A is secreted mainly byactivated CD4+ and CD8+ T lymphocytes and acts through itsreceptor, IL-17R, to induce the expression of many mediators ofinflammation, most importantly, those that are involved in theproliferation, maturation and chemotaxis of neutrophils. Elevated levels of IL-17A have been associated with severalconditions, including rheumatoid arthritis, airway inflammation,allograft rejection, inflammatory boweldisease, psoriasis, cancerand multiple sclerosis. Human, mouse and rat IL-17A showactivity on mouse cells. Recombinant mouse IL-17A is anon-glycosylated, disulfide-linked homodimer, containing two 134amino acid subunits and having a total molecular mass of 30 kDa.
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自1985年成立以来,Gemini生物产品一直致力于生产始终如一的高品质产品,并提供卓越的个性化服务。该公司开始在加利福尼亚州的卡拉巴斯开展业务,营销活动的目标是整个加州的研究和生物技术界。由于不断取得进步的成功,Gemini不断扩大销售队伍,能够为整个美国服务。在经历了多次扩张之后,Gemini现在在加利福尼亚州西萨克拉门托的12000平方英尺的制造工厂中运营。
如今,Gemini是学术研究、生物技术、细胞和基因治疗以及生物制药行业中领先的细胞培养基、血清和其他试剂的制造商和供应商。一支全国性的销售队伍和一个国际分销网络服务于全世界的细胞培养实验室。
2018年9月,医疗私人股本公司Belhealth Investment Partners投资双子座生物产品。由首席执行官戴尔•戈登(DaleGordon)领导的新的领导团队将带领公司进入激动人心的下一章。随着这项增长性投资,Gemini计划在2020年初前在萨克拉门托西部新建一座25000平方英尺的设施。
在其成长过程中,Gemini一直保持着建立其声誉的个性化服务。样品和订单通常在要求的同一天进行处理和装运,使客户能够在第二天收到订单。Gemini的销售团队定期拜访客户,为客户需求提供双方同意的解决方案。今天,我们为我们在Gemini所提供的独特产品感到骄傲:价格有竞争力的产品,经过广泛测试,在过去的34年中被证明是高质量的,再加上业内无与伦比的服务。